Huntington’s chorea – Neurodegenerative disease of brain

Huntington's chorea – Neurodegenerative disease of brain

Huntington’s chorea – Neurodegenerative disease of brain.
 
It is characterized by irregular and uncontrolled body movements. It is transmitted from parent to child on a normal chromosome, with only one mutant allele needed to get the disease. The disease can manifest itself not only in a physical way. It also has an impact on the mental health of the patient, as it causes a decrease in mental functions. The physical symptoms of chorea develop very slowly and can appear at any age (most often between the ages of 20 and 40).

Although it is not a fatal disease, it clearly weakens the immune system and reduces life expectancy. During the disease, the neurons of the caudate nucleus, co-responsible for motor coordination, disappear. The first symptoms include, among others, deterioration of concentration and organization of thoughts, slow thinking and dementia. The disease first attacks the smaller and more delicate muscles that control the tongue, throat, and lungs. Huntington’s chorea is one of the rarest diseases in the world. It affects 7 people out of 100,000.

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