Naked mole – rat – Heterocephalus glaber

Naked mole-rat - Heterocephalus glaber - EatingNaked mole-rat - Heterocephalus glaberHeterocephalus glaber - Louisville-ZooHeterocephalus glaber - Museum of Natural History - Genova, Italy

Naked mole-rat – Heterocephalus glaber

Naked mole-rat – Heterocephalus glaber – Is practically blind and has no pain. This rodent lives in East Africa. It is digging underground corridors in search of tubers and roots. For this he uses the incisors that are in front of the lips, so that the soil does not get into the mouth.
Mole-rats spend almost their entire lives underground without going to the surface. They are unusual for many reasons. Not only are they the only cold-blooded mammals, they are also resistant to cancer, aging, hypoxia and pain.
Their almost completely hairless, thick and wrinkled skin. It is insensitive to abrasions or scratches. Because Mole-rats do not have the key neurotransmitter for pain conduction (substance P).

Naked mole-rats are the longest-living rodents (they live to 30 years)

And their risk of death doesn’t increase with age. These animals have very active mechanisms repair DNA.
They also tolerate extreme hypoxia, which often occurs in narrow and stuffy underground tunnels. When there is a lack of air, mole-rats reduce life activity. They change the energy supply process (break down fructose instead of glucose). In this way they avoid brain damage.
The equally interesting is structure Social. Which resembles swarms of bees or ant colonies. Flocks of these rodents count from several dozen to 300 individuals. At the same time, only the queen and prolific male breeds. The rest are sterile and conscientiously work for the herd.

Synthetic exendin – Previously only from saliva

Synthetic exendin - Arizona Gila monster (Heloderma suspectum)

Synthetic exendin – Previously only from saliva

Synthetic exendin – Eli Lilly & Co. has developed synthetically exendin – 4. Previously only obtainable from the saliva of the Gila monster (Heloderma suspectum) – one of two venomous lizards in the world. Living in the deserts of the northwestern Mexico and south western United States. During the manufacturing process used the latest methods of biogenetics. Exendin is intended for the treatment of type 2 diabetes has become a forerunner in a new series of drugs known as mimetic (imitation) incretin. They imitate the action of incretin hormones found in nature. In addition to the pancreas incretins also affect other organs in connection with the regulation of glucoseliver, kidney, muscle and brain.